Stem cell 'immortality' gene found (New Scientist)

幹細胞

The gene found in mouse ESCs and some human equivalents appears to be the "master gene", co-ordinating other genes to allow stem cells to multiply limitlessly while still retaining their ability to differentiate. It has been christened Nanog after the land in Celtic myth called Tir nan Og, whose inhabitants remain forever young.

奈良先端科学技術大学院大学の山中伸弥助教授らのチームも独立に同じ発見。セル誌に並んで掲載。

  • Mitui et al.(2003) "The Homeoprotein Nanog Is Required for Maintenance of Pluripotency in Mouse Epiblast and ES Cells" [Abstract]
  • Chambers et al.(2003) "Functional Expression Cloning of Nanog, a Pluripotency Sustaining Factor in Embryonic Stem Cells" [Abstract]

Washington Postに関連記事あり。